Chapter 1
Optical Technology until the Year 2000: An Historical Overview OTTO S. WOLFBEIS
1 Introduction
2 Very Early History
3 Early History (up to about 1985)
4 Optical Sensors for Gases (Including Dissolved Gases) and Organics
5 Opt(r)odes for pH
6 Optical Sensors for Ions
7 Enzyme-Based Biosensors
8 Fiber Optic Systems
9 Signal Referencing
10 Optical Sensing Schemes
11 Materials for Optical Chemical Sensors and Biosensors
12 Imaging and Pressure-Sensitive Paints
13 Commercial Instrumentation Using Opt(r)odes
References
Chapter 2 Molecularly Imprinted Polymers for Optical Sensing Devices
MARTA ELENA Df Az-GARcfA, ROSANA BADfA
1 Introduction
2 Molecular Imprinting Process
2.1 Covalent Molecular Imprinting
2.2 Self-assembly Molecular Imprinting
3 Polymer Composition
3.1 Templates
3.2 Type of Monomer and Crosslinker
3.3 Porogenic Solvents
3.4 Radical Initiators
4 MIP Optical Sensing Applications
4.1 Optical Sensing Approaches for Metals of Environmental Concern
4.1.1 Imprinted Metal Ion Sensors Based on Polymerizable Metal Chelates (Covalent Imprinting)
4.1.2 Optical Sensors Based on Non-covalent Imprinting of Fluorescent Metal Chelates
4.2 Optical Sensing Approaches for Environmental Harmful Compounds
4.3 MIP Optical Sensing Materials for Organic Volatile Compounds
5 Conclusions and Outlook
References
Chapter 3 Chromogenic and Fluorogenic Reactands: New Indicator Dyes for Monitoring Amines, Alcohols and Aldehydes
GERHARD J. MOHR
1 Introduction
2 Sensing Amines
2.1 Trifluoroacetylazobenzene Dyes
2.2 Trifluoroacetylazobenzene Copolymers
3 Sensing Alcohols
3.1 Trifluoroacetylstilbenes
4 Sensing Aldehydes
4.1 Perylene Tetracarboxylbisimides
5 Conclusions and Outlook
References
Chapter 4 Design, Quality Control and Normalization of Biosensor Chips
CLAUDIA PREININGER, URSULA SAUER
1 Introduction
2 Principle
3 Biochip Fabrication
3.1 Biomolecular Probes
5.2 Array Manufacture
3.3 Slides and Immobilization
4 Optical Read-out
5 Quality Control
5.1 Autofluorescence
5.2 Arraying
5.3 Print buffer
5.4 Immobilization
5.5 Fluorescent Label
5.6 Validation
6 Data Collection and Analysis
6.1 Imaging
6.2 Imaee Analysis
……
Chapter 5 Rapid, Multiplex Optical Biodetection for Point-of-Care Applications
Chapter 6 Multi-functional Biochip for Medical Diganostics and Pathogen Detection
Chapter 7 Surface Plasmon Resonance Biosensors for Food Safety
Chapter 8 NIR Dyes for Ammonia and HCI Sensors
Chapter 9 Piezo-Optical Dosimeters for Occupational and Environmental Montoring
Chapter 10 Interferometric Biosensors for Environmental Pollution Detection
Chapter 11 Fibre-optic Sensors for Humidity Monitoring
Chapter 12 Optical Sensing of pH Low lonic Strength Waters
Chapter 13 Environmental and Industrial Optosensing with Tailored Luminescent Ru(II) Polypyridyl Complexes
Chapter 14 TIFR Array Biosensor for Enviromental Monitoring
Chapter 15 Optical Techniques for Determination and Sensing of Hydrogen Peroxide in Industrial and Environmental Smaples
Subject Index
