內容簡介

Edited by Romano (senior principal life scientist, Science Applications International Corporation), Lukey (commander of the US Army Medical Research Institute of Chemical Defense), and Salem (chef scientist for life sciences, US Army Edgewood Chemical Biological Center), this volume discusses methods and products for preventing, diagnosing, and treating the acute and chronic effects of exposure to toxic chemical warfare agents, focusing on key developments in the field since 2001. Following a brief history of chemical warfare, 24 chapters address the chemistry of chemical warfare agents; chemical warfare agent threats to drinking water; health effects of low-level exposure to nerve agents; toxicokinetics of nerve agents; application of genomic, proteomic, and metabolomic technologies to the development of countermeasures against chemical warfare agents; novel approaches to medical protection against chemical warfare nerve agents; progress in development of a new mode of protection against organophosphorous exposure; in vitro suppression of amyloid fibril formation by butyrylcholinesterase and its synthetic c-terminal peptide; inhalation toxicology of nerve agents; vesicants and oxidative stress; health effects of exposure to vesicant agents; toxicology, clinical presentation, and medical management of cyanides; mechanism of action of botulinum neurotoxin and medical countermeasures; ricin and related toxins; clinical detection of exposure to chemical warfare agents; personal protective equipment; chemical warfare agent decontamination from skin; chemical warfare and terrorism and traumatic stress responses; domestic preparedness, first response, and public health considerations with regards to emergency response to a chemical warfare agent incident; and emergency medical response to a chemical terrorist attack. Annotation 穢2008 Book News, Inc., Portland, OR (booknews.com)
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